DDAH 2 maintains blood pressure and kidney function in response to ADMA administration in both control and diabetic rats
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چکیده
منابع مشابه
Insufficient insulin administration to diabetic rats increases substrate utilization and maintains lactate production in the kidney
Good glycemic control is crucial to prevent the onset and progression of late diabetic complications, but insulin treatment often fails to achieve normalization of glycemic control to the level seen in healthy controls. In fact, recent experimental studies indicate that insufficient treatment with insulin, resulting in poor glycemic control, has an additional effect on progression of late diabe...
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Endothelium-derived nitric oxide (NO) is vasoprotective, as it enhances endothelial cell survival and proliferation, inhibits the excessive proliferation of vascular smooth muscle cells, and suppresses the adhesion of platelets and inflammatory cells to the vessel wall.1 Substantial evidence from preclinical studies and human research indicates that impairment of the endothelial NO synthase (NO...
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Central administration of acetylcholine or nicotine to rats induces changes in blood pressure and heart rate via central chol inoceptor activation (1, 2). Physostigmine a cholinesterase inhibitor also modifies blood pressure and heart rate (3, 4). Thus, central cholinergic mechanisms may be physio logically involved in the central control of cardiovascular function. In the present experiments, ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.1059.29